Modulation of Tenoxicam Release from Hydrophilic Matrix: Modulator Membrane versus Rate-Controlling Membrane

Modulation of drug release from hydrophilic matrices

Fabrication of ultrathin graphene oxide-coated membrane with hydrophilic properties for arsenate removal from water

Terms and conditions of current drinking water quality standards, including reducing the maximum arsenic concentration from 50 μgl-1 to 10 μgl-1 and predicted stricter standards in future, reveals the necessity for development of new technologies. This study aimed to prepare and evaluate a new nanocomposite membrane using graphene oxide (GO) thin layer to remove arsenic (v) from water. To fabri...

Evaluation of Ocimum basilicum L. seed mucilage as rate controlling matrix for sustained release of propranolol HCl

Polysaccharide mucilage derived from the seeds of Ocimum basilicum L. (family Lamiaceae) was investigated for use in matrix formulations containing propranolol hydrochloride. Basil mucilage was extracted and several tablets were formulated. The effect of mucilage on drug release rate was evaluated in comparison with tablets containing two kinds of hydroxypropyl methylcellulose (HPMC K4M and HPM...

Pretreatment and Membrane Hydrophilic Modification to Reduce Membrane Fouling

The application of low pressure membranes (microfiltration/ultrafiltration) has undergone accelerated development for drinking water production. However, the major obstacle encountered in its popularization is membrane fouling caused by natural organic matter (NOM). This paper firstly summarizes the two factors causing the organic membrane fouling, including molecular weight (MW) and hydrophili...

Bilayer Membrane Modulation of Membrane Type 1 Matrix Metalloproteinase (MT1-MMP) Structure and Proteolytic Activity

Cell surface proteolysis is an integral yet poorly understood physiological process. The present study has examined how the pericellular collagenase membrane-type 1 matrix metalloproteinase (MT1-MMP) and membrane-mimicking environments interplay in substrate binding and processing. NMR derived structural models indicate that MT1-MMP transiently associates with bicelles and cells through distinc...